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Long-term NMN supplementation safety in humans

Phase I trial demonstrating chronic NMN supplementation (250-500mg/day for 12 weeks) is safe and well-tolerated, with no significant adverse effects in healthy adults.

Safety Profile

  • No serious adverse events
  • No significant lab abnormalities
  • Well-tolerated at all doses

NAD+ Elevation

Sustained elevation of blood NAD+ without tachyphylaxis.

Outcomes

  • safety-profile
    No serious adverse events; no significant lab abnormalities; well-tolerated at 250-500mg/day for 12 weeks
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