Impact of different doses of cold water immersion (duration and temperature variations) on recovery from acute exercise-induced muscle damage: a network meta-analysis
2025 systematic review and network meta-analysis (55 RCTs) comparing cold-water immersion dose bands (duration × temperature) for delayed-onset muscle soreness, jump performance, and creatine kinase after exercise-induced muscle damage.
Why this matters
Adds a dose-ranking lens on post-exercise cold-water immersion—complements conventional pairwise DOMS meta-analyses (e.g. Bleakley 2023 on this wiki) by explicitly comparing short vs medium vs long immersion at low vs medium vs high temperature bins.
Design (high level)
- Trials: 55 RCTs (2000–Sep 2024 searches)
- Endpoints: DOMS (42 trials), jump performance (36), creatine kinase (30)
- Analysis: network meta-analysis vs passive control
Pooled vs-control highlights (significant network estimates reported by authors)
- DOMS: MD-MT-CWI (10–15 min, 11–15 °C) SMD −1.45 (95% CI −2.13 to −0.77; p < 0.01); MD-LT-CWI (10–15 min, 5–10 °C) SMD −1.12 (95% CI −1.78 to −0.47; p = 0.01)
- Jump performance: MD-LT-CWI SMD +0.48 (0.20–0.77; p = 0.01); MD-MT-CWI SMD +0.42 (0.15–0.70; p = 0.02)
- Creatine kinase: MD-MT-CWI SMD −0.85 (−1.36 to −0.35; p = 0.01); MD-LT-CWI SMD −0.90 (−1.46 to −0.34; p = 0.02)
Authors’ ranking caveat
SUCRA-style rankings favored MD-LT-CWI for jump + CK and MD-MT-CWI for DOMS—interpret alongside heterogeneity, sport specificity, and hypertrophy-interference literature not primary in this network.
Protocol map
Cold water immersion (cold-plunge) only—not interchangeable with short cold-shower add-ons (cold-exposure).
Outcomes
- Delayed Onset Muscle Soreness at 24 hours-1.45SMD (Standardized Mean Difference)
- Effect Size (Cohen's d / SMD)0.48d (Cohen's d)
- Effect Size (Cohen's d / SMD)-0.9d (Cohen's d)