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Nicotinamide riboside raises NAD+ safely in humans
Phase I/II trial demonstrating NR supplementation (100-500mg/day) safely elevates NAD+ levels in healthy adults, with no significant adverse effects at any dose.
NAD+ Elevation
- 100mg: 40% increase
- 300mg: 100% increase
- 500mg: 200% increase
Safety
No serious adverse events; mild GI symptoms at highest dose.
Outcomes
- NAD+ Level100