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The effect of heat therapy on blood pressure and peripheral vascular function: A systematic review and meta-analysis

Systematic review and meta-analysis (15 studies): passive heat therapy reduced mean arterial pressure (−5.86 mmHg), systolic BP (−3.94 mmHg), and diastolic BP (−3.88 mmHg) versus control and improved brachial flow-mediated dilation (+1.95%) in pooled models (healthy and clinical populations).

Design

  • SR + MA; 15 included studies after screening 4522 titles (search through Sep 2020)
  • Intervention: passive heat sessions (≈30–90 min) over ≈10–36 exposures (sauna / hot bath / water immersion trials)
  • GRADE: moderate certainty for BP and HR domains in abstract framing

Pooled vs control (abstract MD [95% CI])

  • Mean arterial pressure (n = 4): −5.86 mmHg (−8.63 to −3.10; P < 0.0001)
  • Systolic BP (n = 10): −3.94 mmHg (−7.22 to −0.67; P = 0.02)
  • Diastolic BP (n = 9): −3.88 mmHg (−6.13 to −1.63; P = 0.0007)
  • Flow-mediated dilation (n = 5): +1.95% (0.14 to 3.76; P = 0.03)
  • Resting HR (n = 10): −1.25 bpm (−3.20 to 0.70; P = 0.21) — not statistically significant

Evidence hygiene

Heterogeneous modes/doses; pooled samples mix healthy and clinical participants—pair with Finnish sauna cohort rows for long-term outcomes, not as duplicate proof.

Publication

Pizzey FK, et al. Exp Physiol. 2021 Jun 106(6):1317-1334. doi: 10.1113/EP089904. PMID 33866630.

Outcomes

  • Systolic Blood Pressure
    -3.94
    mmHg (Millimetres of Mercury)
  • Diastolic Blood Pressure
    -3.88
    mmHg (Millimetres of Mercury)
  • Endothelial Function
    1.95
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