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Mitochondrial dynamics and exercise adaptation
Review demonstrating exercise promotes mitochondrial fusion and biogenesis, improving mitochondrial quality and metabolic flexibility through PGC-1α activation.
Mitochondrial Adaptations
- Mitochondrial fusion: increased
- PGC-1α expression: 2-3x
- Mitochondrial quality: significantly improved
Exercise Prescription
Both endurance and resistance training effective; 3-5 sessions/week.
Outcomes
- PGC-1α Expression2.5