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Mitochondrial dynamics and exercise adaptation

Review demonstrating exercise promotes mitochondrial fusion and biogenesis, improving mitochondrial quality and metabolic flexibility through PGC-1α activation.

Mitochondrial Adaptations

  • Mitochondrial fusion: increased
  • PGC-1α expression: 2-3x
  • Mitochondrial quality: significantly improved

Exercise Prescription

Both endurance and resistance training effective; 3-5 sessions/week.

Outcomes

  • PGC-1α Expression
    2.5
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