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Time-restricted feeding for prevention of metabolic disease
Foundational review summarizing rodent data and early human pilots demonstrating isocaloric time-restricted feeding improves metabolic health independent of weight loss.
Take-away Messages
- Aligning food intake with active phase preserves clock-gene oscillation
- Human translation requires well-powered RCTs but early data promising
- Eating windows of 8-12 hours most studied
Outcomes
- Systolic Blood Pressure-3.1mmHg (Millimetres of Mercury)