← All sources
Nutritional interventions to augment resistance training-induced skeletal muscle hypertrophy
Narrative review (Front Physiol, 2015) synthesising how resistance exercise and post-exercise protein feeding jointly amplify muscle protein synthesis (MPS) and, over time, skeletal muscle hypertrophy—with emphasis on protein dose, source, distribution, and training variables.
Scope
Narrative / mechanistic synthesis (not a pooled meta-analysis of hypertrophy RCTs).
Core mechanistic claim
MPS is framed as the primary locus driving net muscle gain because it is more responsive than MPB to acute changes in protein feeding and loading.
Practical synthesis (as written in the paper)
- Resistance exercise (RE) followed by protein ingestion augments RE-induced MPS.
- RE variables (frequency, volume, time under tension, training status) modulate the MPS response.
- Protein manipulation during recovery (dose, source, distribution/timing) is discussed as a lever on the adaptive response.
Evidence hygiene
Use next to protein-distribution RCTs and hypertrophy outcome trials on Resistance training (resistance-training)—this row is physiology + integration, not a replacement for long-term lean-mass effect sizes.
Outcomes
- Review frames post-resistance-exercise protein ingestion as augmenting MPS and, over repeated sessions, supporting skeletal muscle hypertrophy; highlights dose/source/distribution/timing as modulators alongside training variables.