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Exercise and metabolic health: molecular mechanisms
Comprehensive review of how acute and chronic exercise improves insulin sensitivity, glucose tolerance, and lipid metabolism through AMPK and mitochondrial adaptations.
Metabolic Benefits
- Insulin sensitivity: 20-40% improvement
- GLUT4 translocation: enhanced
- AMPK activation: key mediator
Training Adaptations
Single session improves insulin sensitivity for 24-72 hours.
Outcomes
- Insulin Sensitivity30