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Comparison between cryotherapy and photobiomodulation in muscle recovery: a systematic review and meta-analysis

Meta-analysis of four RCTs (66 healthy adults) comparing isolated post-exercise photobiomodulation with cryotherapy: pooled estimates favored photobiomodulation for strength recovery, DOMS, and muscle-damage biomarkers; oxidative stress and inflammatory markers did not differ.

Pooled effects (PBMT vs cryotherapy)

  • Peak torque / strength recovery: SMD 1.73 (95% CI 1.33–2.13; I² = 27%; p < 0.00001)
  • DOMS: MD −25.69% (95% CI −34.42 to −16.97; I² = 89%)
  • Muscle-damage biomarkers: SMD −1.48 (95% CI −1.93 to −1.03)
  • Oxidative stress / inflammation: no clear pooled difference

Interpretation for cold-plunge users

Shows relative performance of two popular recovery tools in small trials—not that cold is harmful. Device access, session timing, and blinding differ across studies; many athletes still prefer cold for convenience and sensory tolerance.

Outcomes

  • Effect Size (Cohen's d / SMD)
    1.73
    d (Cohen's d)
  • Perceived Muscle Soreness
    -25.69
    % (Percent Change)
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