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Effect of Yoga and Walking on Glycemic Control for the Management of Type 2 Diabetes: A Systematic Review and Meta-analysis

PRISMA systematic review of 16 RCTs (n=1820) in type 2 diabetes on oral hypoglycemic therapy: versus control, yoga produced larger mean reductions in fasting glucose, postprandial glucose, HbA1c, fasting insulin, and HOMA-IR than walking; walking still beat control for fasting glucose and HbA1c.

Design

  • SR + MA (RevMan); PROSPERO CRD42022310213
  • 16 RCTs; n = 1820; ages 17–75 y; all on OHA
  • Arms: yoga, walking, control (no regular exercise)

Yoga vs control (abstract mean differences)

  • FBG: −31.98 mg/dL (95% CI −47.93 to −16.03)
  • PPBG: −25.59 mg/dL (−44.00 to −7.18)
  • HbA1c: −0.73% (−1.24 to −0.22)
  • Fasting insulin: −7.19 μIU/mL (−12.10 to −2.28)
  • HOMA-IR: −3.87 (−8.40 to −0.66)

Walking vs control

  • FBG: −12.37 mg/dL (−20.06 to −4.68)
  • HbA1c: −0.35% (−0.70 to −0.01)

Yoga vs walking (head-to-head abstract contrasts)

  • FBG and HbA1c favoured yoga; fasting insulin / HOMA-IR contrasts crossed null in abstract CIs—read forest plots before overclaiming insulin superiority.

Publication

Dhali B, Chatterjee S, Sundar Das S, et al. J ASEAN Fed Endocr Soc. 2023;38(2):113-122. PMID 38045671.

Outcomes

  • HbA1c (Glycated Hemoglobin)
    -0.73
    % (Absolute Change)
  • HbA1c (Glycated Hemoglobin)
    -0.35
    % (Absolute Change)
  • Yoga vs control fasting glucose −31.98 mg/dL (95% CI −47.93 to −16.03); walking vs control −12.37 mg/dL (−20.06 to −4.68) per abstract.
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