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Protein intake timing and muscle protein synthesis

Meta-analysis showing 20-40g protein per meal maximizes muscle protein synthesis, with 4-5 feedings daily optimizing daily synthesis rates in resistance-trained individuals.

Protein Synthesis

  • Per meal: 20-40g optimal
  • Leucine threshold: 2.5-3g
  • MPS duration: 3-4 hours post-ingestion

Distribution

Even distribution (4-5 meals) superior to skewed protein intake.

Outcomes

  • muscle-protein-synthesis
    20-40g protein per meal maximizes MPS; leucine threshold 2.5-3g; even distribution of 4-5 feedings optimal
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