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Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis

2025 PLOS ONE systematic review and meta-analysis of 11 RCTs (n=3,177 healthy adults): acute cold-water immersion (≤15 °C, ≥30 s; mostly baths, one shower trial) showed large acute increases in pooled inflammation markers immediately and 1 h post-exposure, a significant reduction in stress at 12 h but not 0–48 h, null pooled immune effects at 0–1 h with narrative mention of longer-term cold-shower sickness-absence benefits, and signals for sleep quality and quality of life but not mood.

Scope

Eligible trials: healthy adults; cold shower, ice bath, or plunge at ≤15 °C for ≥30 s (acute or longer programs).

Pooled quantitative highlights (random-effects SMDs, pre vs post CWI)

  • Inflammation markers: SMD +1.03 immediately post (95% CI 0.37–1.68; p < 0.01); SMD +1.26 at 1 h post (95% CI 0.59–1.94; p < 0.01) — authors frame as acute inflammatory response, not long-term chronic inflammation reduction.
  • Stress: SMD −1.00 at 12 h post (95% CI −1.40 to −0.61; p < 0.01); no significant pooled stress change at 0, 1, 24, or 48 h.
  • Immune function (immediate / 1 h): pooled not significant.

Narrative / secondary themes

  • Sickness absence: narrative synthesis cites about 29% lower absence among cold-shower users — overlaps the standalone Buijze 2016 shower RCT indexed on this wiki; treat as supporting context, not a second independent primary estimate.
  • Sleep quality & quality of life: directional improvements reported in synthesis; mood outcomes did not show a pooled signal.

How to use alongside other entries

  • Cold exposure therapy (cold-exposure): shower-inclusive evidence and pragmatic Buijze anchor.
  • Cold water immersion (cold-plunge): most included trials were baths.
  • Cold exposure & inflammation (cold-exposure-inflammation): acute marker increases here differ from chronic inflammatory-disease RCTs (e.g. metabolic syndrome cold acclimation) — keep time course in mind.

Limitations (authors)

Few RCTs, small individual trial sizes, limited population diversity; PROSPERO CRD42024500591.

Outcomes

  • Effect Size (Cohen's d / SMD)
    1.03
    d (Cohen's d)
  • Effect Size (Cohen's d / SMD)
    1.26
    d (Cohen's d)
  • Effect Size (Cohen's d / SMD)
    -1
    d (Cohen's d)
  • Narrative synthesis: ~29% reduction in sickness absence among cold-shower participants (ties to Buijze-style outcomes; not a separate pooled IRR in this paper).
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