Health Protocols — Evidence-Based Health Research

Systematic review/meta-analysis (26 studies: 18 acute, 8 chronic) finds chronic resistance training lowers 24-hour and daytime ambulatory systolic/diastolic blood pressure in adults with chronic diseases (e.g. 24-h SBP −3.99 mmHg, DBP −1.52 mmHg), with smaller acute daytime diastolic effects; risk of bias was often unclear/high.

Design

Corpus: 26 crossover / controlled trials (18 acute, 351 participants; 8 chronic, 356 participants)
Comparator: resistance exercise vs control / control condition
Endpoint: ambulatory BP (ABPM)
Search: inception → May 2025

Chronic training — 24 h BP (abstract significant means)

24-h SBP: −3.99 mmHg (95% CI −7.59 to −0.39; p = 0.030)
24-h DBP: −1.52 mmHg (−2.67 to −0.37; p = 0.009)

Chronic training — daytime BP in chronic disease cohorts

Daytime SBP: −5.53 mmHg (−8.83 to −2.23; p = 0.001)
Daytime DBP: −1.86 mmHg (−3.11 to −0.61; p = 0.003)

Acute session signals

24-h DBP (chronic disease): −1.15 mmHg (−2.08 to −0.22; p = 0.020)
Daytime DBP (healthy): −0.77 mmHg (−1.51 to −0.03; p = 0.040)

Evidence hygiene

RoB commonly unclear/high—treat magnitudes as hypothesis-supporting, not clinic titration rules; pair with office-BP meta-analyses on exercise-and-mitochondria context rows.

Publication

Braghieri HA, Brito ADS, Ritti-Dias RM, et al. Int J Sports Med. 2026 Mar. Epub ahead of print. PMID 40840538.